Prof. Gary Black BSc PhD (CNAA)
BSc (Hons) in Applied Biology (1988)
PhD in Molecular Biology/Biochemistry (1992)
Research and Development Interests:
expression of recombinant enzymes in Escherichia coli & Pichia pastoris and their biochemical and structural characterisation
proteomic and metabolomic analysis of prokaryoates
analysis of recombinant protein heterogeneity
I am interested in the use of genomic and metagenomic data to discover novel enzyme specificities and activities, and the subsequent use of mutagenesis methods for optimization. I have expertise in a number of different enzyme groups including nitrile active enzymes, carbonyl reductases, carbohydrate active enzymes, and cytochrome P450s. My group uses a pair of Thermo Q-Exactives to perform proteomic and metabolomic analyses to follow the biochemistry of model organisms.
Dr Justin Perry BA MA PhD
BA. MA (Cantab) in Natural Sciences (1990), Part II in Chemistry
PhD (Trinity College, Dublin) (1995) in synthetic and analytical chemistry
Research and Development Interests
- Biocatalysis: the development of biocatalytic synthetic methods (specifically the nitrile active enzymes), novel assays and instrumental analytical techniques for industrial biotechnology.
- Active Materials: the development of new technology for controlled release from polymers, inhibition of biofouling by active polymers, development of novel synthetic methods, the use of 3D printing technology for the creation of tailored chemical technology, use of biomaterials for petrochemical replacement.
- Inks, Dyes and Pigments:the development of new inks and dyes, and the microanalysis of paint samples from historic objects.